DL-erythro-Dihydrosphingosine

DL-erythro-Dihydrosphingosine is a potent inhibitor of PKC and phospholipase A2 (PLA2) [1][2].

Product Specifications

CAS Number

[3102-56-5]

UNSPSC

12352211

Target

Phospholipase; PKC

Type

Reference compound

Related Pathways

Epigenetics; Metabolic Enzyme/Protease; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dl-erythro-dihydrosphingosine.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCC[C@H](O)[C@H](N)CO

Molecular Formula

C18H39NO2

Molecular Weight

301.52

References & Citations

[1]R Chao, et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25;267 (33) :23459-62.|[2]Hiroyuki Nakamura, et al. Inhibition of arachidonic acid release and cytosolic phospholipase A2 alpha activity by D-erythro-sphingosine. Eur J Pharmacol. 2004 Jan 19;484 (1) :9-17.