SB-224289
SB-224289 is a selective 5-HT1B receptor antagonist, with anxiolytic effect[1].
Product Specifications
CAS Number
180083-23-2
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb-224289.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C2=CC=C(C3=NOC(C)=N3)C=C2C)C=C1)N4CCC5=C4C=C6C(OCC67CCN(C)CC7)=C5
Molecular Formula
C32H32N4O3
Molecular Weight
520.62
References & Citations
[1]Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS One. 2016 May 16;11 (5) :e0154932.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor
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