CGS 12066 (dimaleate)
CGS 12066 (dimaleate) dimaleate is a selective 5-HT1B receptor agonist with an IC50 of 51 nM[1].
Product Specifications
CAS Number
[109028-10-6]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cgs-12066-dimaleate.html
Solubility
10 mM in DMSO
Smiles
FC(C1=CC2=C(N3C(C(N4CCN(C)CC4)=N2)=CC=C3)C=C1)(F)F.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
Molecular Formula
C25H25F3N4O8
Molecular Weight
566.48
References & Citations
[1]Neale RF, et al. Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonist. Eur J Pharmacol. 1987 Apr 7;136 (1) :1-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3
Curated Selection
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