Metaphit
Product Specifications
UNSPSC Description
Metaphit is a specific PCPantagonist and site-directed acylating agent of the [3H]phencyclidine binding site in rat brain homogenates[1]. Metaphit prevents PCP-induced locomotor behavior through presynaptic mechanisms[2].
Target Antigen
iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/metaphit.html
Solubility
10 mM in DMSO
Smiles
S=C=NC1=CC(C2(N3CCCCC3)CCCCC2)=CC=C1
Molecular Weight
300.46
References & Citations
[1]E D French, et al. Metaphit, a proposed phencyclidine (PCP) antagonist, prevents PCP-induced locomotor behavior through mechanisms unrelated to specific blockade of PCP receptors. Eur J Pharmacol. 1987 Aug 21;140(3):267-74|[2]M F Rafferty, et al. A specific acylating agent for the [3H]phencyclidine receptors in rat brain. FEBS Lett. 1985 Feb 25;181(2):318-22.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100998/Metaphit-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100998/
Clinical Information
No Development Reported
CAS Number
96316-00-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Polyclonal BirA Antibody [DyLight 594]](https://cdn.genprice.uk/genprice/genprice4.png)
