U-54494A
Product Specifications
UNSPSC Description
U-54494A is a benzamide derivative related to κ-opioid receptor agonists, U-54494A has an anticonvulsant activity[1].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/u-54494a.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C(N([C@@H]2[C@H](N3CCCC3)CCCC2)C)=O)C=C1Cl.Cl
Molecular Weight
391.76
References & Citations
[1]Fischer, et, al. Anticonvulsant and related effects of U-54494A in various seizure tests. J Pharmacol Exp Ther. 1993, 267, 1.|[2]G De Sarro, et, al. Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex. Gen Pharmacol. 1993, 24, 2.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100963/U-54494A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100963/
Clinical Information
No Development Reported
CAS Number
112465-94-8
Curated Selection
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