U-54494A
U-54494A is a benzamide derivative related to κ-opioid receptor agonists, U-54494A has an anticonvulsant activity[1].
Product Specifications
CAS Number
112465-94-8
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/u-54494a.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C(N([C@@H]2[C@H](N3CCCC3)CCCC2)C)=O)C=C1Cl.Cl
Molecular Formula
C18H25Cl3N2O
Molecular Weight
391.76
References & Citations
[1]Fischer, et, al. Anticonvulsant and related effects of U-54494A in various seizure tests. J Pharmacol Exp Ther. 1993, 267, 1.|[2]G De Sarro, et, al. Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex. Gen Pharmacol. 1993, 24, 2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
OR110826 1 Each
5,6-Dihydro-4H-cyclopenta[b]thiophene-2-carbonyl chloride
Sign In for Pricing
View Details 