NPC 200
NPC 200 is a potent and selective antagonist of Adenosine A1 Receptor. NPC 200 reverses NECA-induced left and right atrial depression with EC50s of 1.08 and 2.03 μM[1].
Product Specifications
CAS Number
85872-53-3
Product Name Alternative
1,3-Dipropyl-8-phenylxanthine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/npc-200.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC)N(CCC)C2=C(N=C(C3=CC=CC=C3)N2)C1=O
Molecular Formula
C17H20N4O2
Molecular Weight
312.37
Precautions
H302, H315, H319, H335
References & Citations
[1]P. V. Kaplita, et al. NPC 205 is a potent and selective adenosine A1, receptor antagonist: Correlation among receptor binding, biochemical, and physiological assays. , 20 (4), 429–443.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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