6-Chloromelatonin
6-Chloromelatonin is a potent melatonin receptor agonist with greater metabolic stability than melatonin. 6-Chloromelatonin compete for [3H]-melatonin and 2-[125I]-iodomelatonin binding to MT1 receptors (pKi=8.9 and 9.1, respectively) . 6-Chloromelatonin compete for [3H]-melatonin binding to MT2 receptors (pKi=9.77) [1][2].
Product Specifications
CAS Number
63762-74-3
UNSPSC
12352005
Hazard Statement
H301-H311-H315-H319-H331-H335-H360
Target
Melatonin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/6-chloromelatonin.html
Solubility
10 mM in DMSO
Smiles
CC(NCCC1=CNC2=C1C=C(OC)C(Cl)=C2)=O
Molecular Formula
C13H15ClN2O2
Molecular Weight
266.72
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MT1; MT2
Frequently Asked Questions
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