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SKF 97541

SKF 97541 (CGP 35024) is a potent and selective GABAB agonist that can induce hyperpotential. SKF 97541 has antiepileptic activity[1][2].

Product Specifications

CAS Number

127729-35-5

Product Name Alternative

CGP 35024

UNSPSC

12352211

Hazard Statement

H302-H318-H410

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/skf-97541.html

Solubility

10 mM in DMSO

Smiles

O=P(C)(CCCN)O

Molecular Formula

C4H12NO2P

Molecular Weight

137.12

Precautions

P264-P270-P273-P280-P330-P391-P501

References & Citations

[1]Bon C, et al. Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro. Br J Pharmacol. 1996 Jun;118 (4) :961-7.|[2]Smirnova EY, et al. Presynaptic GABAB receptors underlie the antiepileptic effect of low-frequency electrical stimulation in the 4-aminopyridine model of epilepsy in brain slices of young rats. Brain Stimul. 2020 Sep-Oct;13 (5) :1387-1395.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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