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SKF 97541

Product Specifications

UNSPSC Description

SKF 97541 (CGP 35024) is a potent and selective GABAB agonist that can induce hyperpotential. SKF 97541 has antiepileptic activity[1][2].

Target Antigen

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/skf-97541.html

Solubility

10 mM in DMSO

Smiles

O=P(C)(CCCN)O

Molecular Weight

137.12

References & Citations

[1]Bon C, et al. Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro. Br J Pharmacol. 1996 Jun;118(4):961-7.|[2]Smirnova EY, et al. Presynaptic GABAB receptors underlie the antiepileptic effect of low-frequency electrical stimulation in the 4-aminopyridine model of epilepsy in brain slices of young rats. Brain Stimul. 2020 Sep-Oct;13(5):1387-1395.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-100915/SKF-97541-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100915/

Clinical Information

No Development Reported

CAS Number

127729-35-5

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