SKF 97541
SKF 97541 (CGP 35024) is a potent and selective GABAB agonist that can induce hyperpotential. SKF 97541 has antiepileptic activity[1][2].
Product Specifications
CAS Number
127729-35-5
Product Name Alternative
CGP 35024
UNSPSC
12352211
Hazard Statement
H302-H318-H410
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/skf-97541.html
Solubility
10 mM in DMSO
Smiles
O=P(C)(CCCN)O
Molecular Formula
C4H12NO2P
Molecular Weight
137.12
Precautions
P264-P270-P273-P280-P330-P391-P501
References & Citations
[1]Bon C, et al. Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro. Br J Pharmacol. 1996 Jun;118 (4) :961-7.|[2]Smirnova EY, et al. Presynaptic GABAB receptors underlie the antiepileptic effect of low-frequency electrical stimulation in the 4-aminopyridine model of epilepsy in brain slices of young rats. Brain Stimul. 2020 Sep-Oct;13 (5) :1387-1395.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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