F1324 (acetate)
F1324 acetate is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC50 of 1 nM. F1324 acetate exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].
Product Specifications
UNSPSC
12352209
Target
Bcl-2 Family
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/f1324-acetate.html
Solubility
10 mM in DMSO
Smiles
[Ac-LWYTDIRMSWRVP-OH(acetate)]
Molecular Formula
C83H121N21O20S.xC2H4O2
Molecular Weight
1765.04 (free acid)
References & Citations
[1]Sakamoto K, et al. Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship. Biochem Biophys Res Commun. 2017 Jan 8;482 (2) :310-316.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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