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F1324 (acetate)

F1324 acetate is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC50 of 1 nM. F1324 acetate exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].

Product Specifications

UNSPSC

12352209

Target

Bcl-2 Family

Type

Peptides

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/f1324-acetate.html

Solubility

10 mM in DMSO

Smiles

[Ac-LWYTDIRMSWRVP-OH(acetate)]

Molecular Formula

C83H121N21O20S.xC2H4O2

Molecular Weight

1765.04 (free acid)

References & Citations

[1]Sakamoto K, et al. Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship. Biochem Biophys Res Commun. 2017 Jan 8;482 (2) :310-316.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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