PrPSc-IN-1
Product Specifications
UNSPSC Description
PrPSc-IN-1 is a fluorescent probe, binds to the misfolded protein PrPSc, inhibits its accumulation, with an IC50 of 1.6 μM. Anti-prion activity[1].
Target Antigen
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/prpsc-in-1.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(N2C(C(N/N=C/C3=C(C=CC=C4)C4=NC=C3)=N5)=CC=C2)C5=C1
Molecular Weight
367.40
References & Citations
[1]Zaccagnini L, et al. Identification of novel fluorescent probes preventing PrPSc replication in prion diseases. Eur J Med Chem. 2017 Feb 15;127:859-873.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100857/PrPSc-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100857/
Clinical Information
No Development Reported
CAS Number
1315475-30-9
Curated Selection
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