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(S)-3-Hydroxyphenylglycine

Product Specifications

UNSPSC Description

(S)-3-Hydroxyphenylglycine ((S)-3HPG) is a potent mGluR1 agonist without effect at mGlu2 or mGlu4[1].

Target Antigen

mGluR

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-3-hydroxyphenylglycine.html

Solubility

10 mM in DMSO

Smiles

O=C(O)[C@@H](N)C1=CC=CC(O)=C1

Molecular Weight

167.16

References & Citations

[1]Y Hayashi, et al.  Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci. 1994 May;14(5 Pt 2):3370-7.|[2]Birse EF, et al. Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience. 1993 Feb;52(3):481-8.

Shipping Conditions

Room temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-100841A/S-3-Hydroxyphenylglycine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100841A/

Clinical Information

No Development Reported

CAS Number

71301-82-1

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