(S) -3-Hydroxyphenylglycine

(S) -3-Hydroxyphenylglycine ((S) -3HPG) is a potent mGluR1 agonist without effect at mGlu2 or mGlu4[1].

Product Specifications

CAS Number

[71301-82-1]

Product Name Alternative

(S) -3HPG

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-3-hydroxyphenylglycine.html

Solubility

10 mM in DMSO

Smiles

O=C(O)[C@@H](N)C1=CC=CC(O)=C1

Molecular Formula

C8H9NO3

Molecular Weight

167.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Y Hayashi, et al. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci. 1994 May;14 (5 Pt 2) :3370-7.|[2]Birse EF, et al. Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience. 1993 Feb;52 (3) :481-8.