5-Iodowillardiine

5-Iodowillardiine is a potent and selective kainate receptor agonist. 5-Iodowillardiine is selective for kainate receptors composed of hGluR5 subunits[1].

Product Specifications

CAS Number

[140187-25-3]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/5-iodowillardiine.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H](N)CN1C(NC(C(I)=C1)=O)=O)=O

Molecular Formula

C7H8IN3O4

Molecular Weight

325.06

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Jane DE, et al. Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes. J Med Chem. 1997 Oct 24;40 (22) :3645-50.