Homoquinolinic acid
Product Specifications
UNSPSC Description
Homoquinolinic acid is a non endogenous agonist of NMDAR2 receptor[1][2].
Target Antigen
iGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/homoquinolinic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CC1=CC=CN=C1C(O)=O
Molecular Weight
181.15
References & Citations
[1]L P de Carvalho, et al. The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochem Int. 1996 Apr;28(4):445-52.|[2]G Woodhall, et al. NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons. J Neurophysiol. 2001 Oct;86(4):1644-51.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100802/Homoquinolinic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100802/
Clinical Information
No Development Reported
CAS Number
490-75-5
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