Homoquinolinic acid

Homoquinolinic acid is a non endogenous agonist of NMDAR2 receptor[1][2].

Product Specifications

CAS Number

[490-75-5]

UNSPSC

12352005

Hazard Statement

H302-H312-H332

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/homoquinolinic-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC1=CC=CN=C1C(O)=O

Molecular Formula

C8H7NO4

Molecular Weight

181.15

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]L P de Carvalho, et al. The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochem Int. 1996 Apr;28 (4) :445-52.|[2]G Woodhall, et al. NR2B-containing NMDA autoreceptors at synapses on entorhinal cortical neurons. J Neurophysiol. 2001 Oct;86 (4) :1644-51.