What is the catalog number for Pirmenol?

The catalog number for Pirmenol is HY-100795.

What sizes are available for Pirmenol?

Pirmenol is available in the following size(s): 5 mg, 10 mg.

How many pack sizes does Pirmenol come in?

Pirmenol is available in 2 different pack sizes.

Is Pirmenol in stock?

Pirmenol is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Pirmenol?

Pirmenol is manufactured by QuantiMol.

What is the estimated delivery time for Pirmenol?

Estimated delivery time for Pirmenol is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Pirmenol?

The safety data sheet for Pirmenol is available here: http://file.medchemexpress.com/batch_PDF/HY-100795/.

Pirmenol

Pirmenol is an orally active antiarrhythmic agent. Pirmenol inhibits IK.ACh (IC50: 0.1 μM) by blocking mAchR. Pirmenol can be used in the research of cardiovascular disease, such as atrial fibrillation[1][2][4].

Product Specifications

CAS Number

68252-19-7

Product Name Alternative

(±) -Pirmenol; CI-845 (free base)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

MAChR; Potassium Channel

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/__plusmn__-Pirmenol.html

Solubility

10 mM in DMSO

Smiles

OC(C1=CC=CC=C1)(CCCN2[C@@H](C)CCC[C@H]2C)C3=CC=CC=N3

Molecular Formula

C22H30N2O

Molecular Weight

338.49

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Watanabe Y, et al. Pirmenol inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart. Eur J Pharmacol. 1997 Oct 29;338 (1) :71-4.|[2]Schardein JL, et al. Preclinical toxicology studies with a new antiarrhythmic agent: Pirmenol hydrochloride (CI-845) . Toxicol Appl Pharmacol. 1980 Nov;56 (2) :294-301.|[3]T Sawanobori, et al. Electrophysiologic and antiarrhythmic actions of pirmenol on rabbit and guinea pig cardiac preparations. J Cardiovasc Pharmacol. 1990 Dec;16 (6) :975-83. |[4]T E Mertz, et al. Pirmenol hydrochloride (CI-845) : antiarrhythmic profile in coronary artery ligated conscious dogs. J Cardiovasc Pharmacol. 1980 Sep-Oct;2 (5) :527-41.