L-AP5

L-AP5 (L-APV; L-2-Amino-5-phosphonovaleric acid) is an NMDA antagonist and is the isomer of D-AP5 (HY-100714A) . L-AP5 shows a relatively weak amino acid and synaptic blocking activity[1].

Product Specifications

CAS Number

[79055-67-7]

Product Name Alternative

L-APV; L-2-Amino-5-phosphonovaleric acid

UNSPSC

12352211

Hazard Statement

H315-H319-H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-ap5.html

Solubility

10 mM in DMSO

Smiles

N[C@@H](CCCP(O)(O)=O)C(O)=O

Molecular Formula

C5H12NO5P

Molecular Weight

197.13

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235 378