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Meta-Fexofenadine

Meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine[1]. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial[2].

Product Specifications

CAS Number

479035-75-1

Product Name Alternative

Meta-MDL-16455; meta-Terfenadine carboxylate

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/meta-fexofenadine.html

Purity

98.63

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(O)C(C)(C)C1=CC=CC(C(O)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2)=C1

Molecular Formula

C32H39NO4

Molecular Weight

501.66

Precautions

H315, H319

References & Citations

[1]Maher HM, et al. Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets. Chem Cent J. 2011 Dec 3;5 (1) :76.|[2]Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4 (3) :367-75.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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