Meta-Fexofenadine
Meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine[1]. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial[2].
Product Specifications
CAS Number
[479035-75-1]
Product Name Alternative
Meta-MDL-16455; meta-Terfenadine carboxylate
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/meta-fexofenadine.html
Purity
98.63
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(O)C(C)(C)C1=CC=CC(C(O)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2)=C1
Molecular Formula
C32H39NO4
Molecular Weight
501.66
Precautions
H315, H319
References & Citations
[1]Maher HM, et al. Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets. Chem Cent J. 2011 Dec 3;5 (1) :76.|[2]Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4 (3) :367-75.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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