(S)-4CPG
Product Specifications
UNSPSC Description
(S)-4CPG ((S)-4-Carboxyphenylglycine) is a potent mGluR2 agonist. (S)-4CPG reduces hyperalgesia and allodynia associated with sciatic nerve contraction injury in rats. (S)-4CPG can be used in research on neurological diseases[1][2].
Target Antigen
mGluR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-4cpg.html
Solubility
10 mM in DMSO
Smiles
N[C@H](C(O)=O)C1=CC=C(C(O)=O)C=C1
Molecular Weight
195.17
References & Citations
[1]Hayashi Y, et al. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes. J Neurosci. 1994 May;14(5 Pt 2):3370-7.|[2]Fisher K, et al. Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 1998 Jul;77(1):59-66.
Shipping Conditions
Room temperature
Storage Conditions
Store at room temperature 3 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100617/S-4CPG-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100617/
Clinical Information
No Development Reported
CAS Number
134052-73-6
Curated Selection
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