Trans-ACBD

Trans-ACBD (trans-1-Aminocyclobutane-1,3-dicarboxylic acid) is a very potent and selective NMDA receptor agonist that modulates glutamatergic neurotransmission[1].

Product Specifications

CAS Number

[117488-23-0]

Product Name Alternative

Trans-1-Aminocyclobutane-1,3-dicarboxylic acid

UNSPSC

12352211

Hazard Statement

H315-H319-H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/trans-acbd.html

Solubility

10 mM in DMSO

Smiles

OC([C@]1(C[C@H](C1)C(O)=O)N)=O

Molecular Formula

C6H9NO4

Molecular Weight

159.14

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]Dimpfel W, et al. Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro. BMC Pharmacol. 2011 Feb 21;11:2.