D-Cl-amidine
D-Cl-amidine is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity[1].
Product Specifications
CAS Number
1404060-15-6
UNSPSC
12352005
Target
Apoptosis; Protein Arginine Deiminase
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/d-cl-amidine.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1
Molecular Formula
C14H19ClN4O2
Molecular Weight
310.78
References & Citations
[1]Bicker KL, et al. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett. 2012 Oct 26;3 (12) :1081-1085.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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