Cloprostenol isopropyl ester

Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+) -Cloprostenol (HY-107381) . Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM[1][2].

Product Specifications

CAS Number

[157283-66-4]

UNSPSC

12352005

Hazard Statement

H302

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/cloprostenol-isopropyl-ester.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=CC(OC[C@H](O)/C=C/[C@@H]2[C@H]([C@H](C[C@H]2O)O)C/C=C\CCCC(OC(C)C)=O)=C1

Molecular Formula

C25H35ClO6

Molecular Weight

466.99

Precautions

P264-P270-P330-P501

References & Citations

[1]Sava A, et, al. Electron microscopic aspects of the effects of certain prostaglandin analogs on mouse testes. Rom J Morphol Embryol. 2015;56 (2 Suppl) :771-5.|[2]Hellberg MR, et, al. Identification and characterization of the ocular hypotensive efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist, and AL-6598, a DP prostaglandin receptor agonist. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S13-33.