Tempol-d17
Tempol-d17 is the deuterium labeled Tempol[1]. Tempol is a general superoxide dismutase (SOD) -mimetic agent that efficiently neutralizes reactive oxygen species (ROS) [2][3].
Product Specifications
CAS Number
100326-46-3
Product Name Alternative
4-Hydroxy-TEMPO-d17
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Autophagy; Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
[O]N(C(C([2H])([2H])[2H])(C1([2H])[2H])C([2H])([2H])[2H])C(C([2H])([2H])[2H])(C([2H])([2H])C1([2H])O)C([2H])([2H])[2H]
Molecular Formula
C9HD17NO2
Molecular Weight
189.35
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Vilar-Pereira G, et al. Resveratrol Reverses Functional Chagas Heart Disease in Mice. PLoS Pathog. 2016 Oct 27;12 (10) :e1005947.|[3]Chatterjee PK, et al. Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat. Kidney Int. 2000 Aug58 (2) :658-73.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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