Eg5 Inhibitor V, trans-24
Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer.
Product Specifications
CAS Number
[869304-55-2]
UNSPSC
12352005
Target
Kinesin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Eg5_Inhibitor_V,_trans-24.html
Purity
98.18
Solubility
DMSO : 45 mg/mL (ultrasonic; warming)
Smiles
O=C([C@]1([H])CC2=C([C@@H](C3=CC=CC(O)=C3)N14)NC5=C2C=CC=C5)N(CC6=CC=CC=C6)C4=O
Molecular Formula
C26H21N3O3
Molecular Weight
423.46
References & Citations
[1]Sunder-Plassmann N, et al. Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. Bioorg Med Chem. 2005 Nov 15;13 (22) :6094-111.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Kinesin-5/Eg5/KSP
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15217359 1 Vial
Lentiviral mouse Calm3 shRNA (UAS) - Lentiviral mouse Calm3 shRNA (UAS, iRFP) (100)
Ask
View Details