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Pipequaline hydrochloride

Product Specifications

UNSPSC Description

Pipequaline hydrochloride (PK-8165 hydrochloride) is a partial benzodiazepine receptor agonist with anxiolytic activity[1][2].

Target Antigen

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pipequaline-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

C1(C2=CC=CC=C2)=NC3=CC=CC=C3C(CCC4CCNCC4)=C1.Cl

Molecular Weight

352.90

References & Citations

[1]Bradwejn J, et al. Effects of PK 8165, a partial benzodiazepine receptor agonist, on cholecystokinin-inducedactivation of hippocampal pyramidal neurons: a microiontophoretic study in the rat. Eur J Pharmacol. 1985 Jun 19;112(3):415-8.|[2]Debonnel G, et al. Pipequaline acts as a partial agonist of benzodiazepine receptors: an electrophysiological study in the hippocampus of the rat. Neuropharmacology. 1987 Sep;26(9):1337-42.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-100140A/Pipequaline-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100140A/

Clinical Information

No Development Reported

CAS Number

80221-58-5

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