Pipequaline hydrochloride
Pipequaline hydrochloride (PK-8165 hydrochloride) is a partial benzodiazepine receptor agonist with anxiolytic activity[1][2].
Product Specifications
CAS Number
80221-58-5
Product Name Alternative
PK-8165 (hydrochloride)
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pipequaline-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
C1(C2=CC=CC=C2)=NC3=CC=CC=C3C(CCC4CCNCC4)=C1.Cl
Molecular Formula
C22H25ClN2
Molecular Weight
352.90
References & Citations
[1]Bradwejn J, et al. Effects of PK 8165, a partial benzodiazepine receptor agonist, on cholecystokinin-inducedactivation of hippocampal pyramidal neurons: a microiontophoretic study in the rat. Eur J Pharmacol. 1985 Jun 19;112 (3) :415-8.|[2]Debonnel G, et al. Pipequaline acts as a partial agonist of benzodiazepine receptors: an electrophysiological study in the hippocampus of the rat. Neuropharmacology. 1987 Sep;26 (9) :1337-42.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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