Calcitriol-13C3

Calcitriol-13C3 is the 13C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.

Product Specifications

Product Name Alternative

1,25-Dihydroxyvitamin D3-13C3

UNSPSC

12352211

Target

Isotope-Labeled Compounds; Sodium Channel

Type

Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/calcitriol-13c3.html

Concentration

12.09 μM * 1 mL in Ethanol

Purity

97.0

Solubility

10 mM in DMSO

Smiles

C=C1[C@H](C[C@@H](C/C1=C/C=C2[C@]3([C@@](C)([C@H](CC3)[C@@H](CCC[13C]([13C])(O)[13C])C)CCC/2)[H])O)O

Molecular Formula

C24 13C3H38O3

Molecular Weight

413.57

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Zhang XF, et al. A-887826 is a structurally novel, potent and voltage-dependent Na (v) 1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats. Neuropharmacology. 2010 Sep;59 (3) :201-7.