Poloxamer 407 (F127)
Product Specifications
UNSPSC Description
Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8? AM and Quest Rhod-4? AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor[1][2].
Target Antigen
LPL Receptor
Type
Biochemical Assay Reagents
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/poloxamer-407.html
Solubility
H2O : 110 mg/mL (ultrasonic)
Smiles
CC.[H(OCH2CH2)x(OCH2CH)y(OCH2CH2)zOH].[CH3]
Molecular Weight
12600(Average)
References & Citations
[1]Antunes FE, et al. Gels of Pluronic F127 and nonionic surfactants from rheological characterization to controlled drug permeation. Colloids Surf B Biointerfaces. 2011 Oct 1;87(1):42-8.|[2]Peng X, et al. Poloxamer 407 Induces Hypertriglyceridemia but Decreases Atherosclerosis in Ldlr-/- Mice. Cells. 2022 May 30;11(11):1795.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D1005/Poloxamer-407-F127-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D1005/Poloxamer-407-F127-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
9003-11-6
Available Sizes
Curated Selection
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