2-Methylcitric acid
2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate[1].
Product Specifications
CAS Number
[6061-96-7]
Product Name Alternative
Methylcitric acid
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-methylcitric-acid.html
Purity
99.72
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
CC(C(O)=O)C(C(O)=O)(O)CC(O)=O
Molecular Formula
C7H10O7
Molecular Weight
206.15
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
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CD44 (HCAM Std., LHR, BA-1, Chondroitin Sulfate Proteoglycan 8, CSPG8, Epican, Extracellular Matrix Receptor III, ECM III, GP90 Lymphocyte Homing Adhesion Receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan Sulfate Proteoglycan, Hermes Antigen, HAS, HUTCH I, Hyaluronate Receptor, Indian Blood Group, Inlu Related p80 GlycoProtein, Ly 24, MDU2, MDU3, MIC4, MUTCH I, Phagocytic GlycoProtein 1, PGP-1) (BSA & Azide Free) (MaxLight 550)
