ML-18
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.
Product Specifications
CAS Number
[1422269-30-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bombesin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ML-18.html
Purity
98.87
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C([C@@H](NC(NC1=CC=C([N+]([O-])=O)C=C1)=O)CC2=CNC3=CC=CC=C23)NCC4(C5=CC=C(OC)C=C5)CCCCC4
Molecular Formula
C32H35N5O5
Molecular Weight
569.65
Precautions
H302, H315, H319, H335
References & Citations
[1]Moody TW, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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