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Recombinant GRP94 Antibody / HSP90B1

Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96) . Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90) . This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp's are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Product Specifications

UniProt

P14625

Reactivity

Human

Immunogen

A recombinant full-length human protein was used as the immunogen for this recombinant GRP94 antibody.

Clonality

Recombinant

Clone

HSP90B1/3168R

Conjugation

Unconjugated

Field of Research

Cell Biology

Purification

Protein A affinity chromatography

Dilution

Flow cytometry: 1-2ug/10^6 cells, Immunohistochemistry (FFPE) : 1-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the recombinant GRP94 antibody should be determined by the researcher.

Tested Applications

FACS, IHC-P

Host or Source

Rabbit

Preservative

0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide

Isotype

Rabbit IgG, kappa

Available Sizes

Frequently Asked Questions

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