Recombinant CD137 Antibody / 4-1BB / TNFRSF9
CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.
Product Specifications
UniProt
Q07011
Reactivity
Human
Immunogen
A human CD137 protein fragment within amino acids 19-188 was used as the immunogen for the recombinant CD137 antibody.
Clonality
Recombinant
Clone
4-1BB/4552R
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT, Western blot: 2-4ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant CD137 antibody should be determined by the researcher.
Tested Applications
IHC-P, WB
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Rabbit IgG, kappa
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
SOX9 / SRY-box 9 (PCRP-SOX9-1A2), CF488A conjugate, 0.1mg/mL
Synaptotagmin 14 (SYT14) (NM_001146264) Human Over-expression Lysate
![[2-[[3-(2-Chlorobenzoyl)-5-ethyl-2-thienyl]amino]-2-oxoethyl]carbamic Acid Benzyl Ester](https://cdn.genprice.uk/products/572/1175270972372/imageurl/trc-c364970-1g.webp)
[2-[[3-(2-Chlorobenzoyl)-5-ethyl-2-thienyl]amino]-2-oxoethyl]carbamic Acid Benzyl Ester
Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker) (IGHM/3776R), CF568 conjugate, 0.1mg/mL
