PAX5 Antibody
The PAX5 gene is a member of thepaired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conservedDNA-binding domain, known as thepaired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute toneoplastic transformation. The PAX5 gene encodes theB-celllineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development andspermatogenesis.
Product Specifications
UniProt
Q02548
Reactivity
Human
Immunogen
Full length human recombinant protein was used as the immunogen for this PAX5 antibody.
Clonality
Monoclonal
Clone
PAX5/2060
Conjugation
Unconjugated
Field of Research
Neuroscience
Purification
Protein G affinity chromatography
Dilution
ELISA (order BSA-free format for coating), Western blot: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the PAX5 antibody should be determined by the researcher.
Tested Applications
ELISA, WB
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Isotype
Mouse IgG1, kappa
Available Sizes
Frequently Asked Questions
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