LAG-3 biner 1
LAG-3 biner 1 (compound 3) is a small molecule ligand (Kd=1.23 μM) for the immune checkpoint lymphocyte activation gene 3 (LAG-3) . LAG-3 biner 1 can be used in the research of cancer diagnosis targeting LAG-3[1].
Product Specifications
CAS Number
1830484-40-6
UNSPSC
12352005
Target
LAG-3
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lag-3-biner-1.html
Purity
97.08
Smiles
O=C(C1=CC(C(O)=O)=CC=C1)NC(CC2)CCN2C3=CC=C(C(F)(F)F)C=N3
Molecular Formula
C19H18F3N3O3
Molecular Weight
393.36
References & Citations
[1]Fuchs, et al. "From Virtual Screens to Cellular Target Engagement: New Small Molecule Ligands for the Immune Checkpoint LAG-3." bioRxiv (2024) : 2024-08.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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