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Drebrin 1 Antibody

Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections. Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS. Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity) . Involved in memory-related synaptic plasticity in the hippocampus (By similarity) . [UniProt]

Product Specifications

UniProt

Q16643

Reactivity

Human

Immunogen

Amino acids 150-281 were used as the immunogen for the Drebrin 1 antibody.

Clonality

Monoclonal

Clone

DRBP1-1

Conjugation

Unconjugated

Field of Research

Alzheimer's, Developmental Biology, Epigenetics, Neuroscience, Signaling Pathways

Purification

Protein G affinity chromatography

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Drebrin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Tested Applications

IHC-P

Host or Source

Mouse

Preservative

0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide

Isotype

Mouse IgG1, kappa

Available Sizes

Frequently Asked Questions

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