APM2 (CT)
Product Specifications
Background
APM2 is an ~8kDa protein which until recently was found only in the EST data base but never as an expressed protein. APM2 has since been shown to be associated with cisplatin resistance in cell lines. APM2 is not found in cisplatin sensitive cell lines. These data implicate APM2 in the development of cisplatin resistance in tumor cells. _x000B_
Synonyms
Adipose most abundant gene transcript 2 Protein, apM-2, APM2, C10orf116
UniProt
Q15847
Conjugation
Unconjugated
Type
Blocking Peptide
Applications
WB
Assay Principle
For use with FXBW7 polyclonal antibodies (Cat. No. X2085P , X2385P).
Stability
See expiration date on vial
Concentration
See vial for Concentration
Form
Provided as solution in phosphate buffered saline
Precautions
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
References & Citations
1. Scott, B.J., et al. APM2 is a novel mediator of cisplatin resistance in a variety of cancer cell types regardless of p53 or MMR status. Int. J. Cancer 2009, 125, 1193-1204
Shipping Conditions
Ambient Temperature, freeze upon arrival
Storage Conditions
Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
Functional Analysis
Antibody Function Blocking
Curated Selection
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