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CD127 Antibody / IL7R

The protein encoded by this gene is a receptor for interleukin 7 (IL7) . The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V (D) J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID) .

Product Specifications

UniProt

P16871

Reactivity

Human

Immunogen

A portion of amino acids 21-236 from the human protein was used as the immunogen for the CD127 antibody.

Clonality

Monoclonal

Clone

IL7R/2751

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Protein G affinity chromatography

Dilution

ELISA: order BSA/sodium azide-free format for coating, Western blot: 1-2ug/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Optimal dilution of the CD127 antibody should be determined by the researcher.

Tested Applications

ELISA, WB

Host or Source

Mouse

Preservative

0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide

Isotype

Mouse IgG2c, kappa

Available Sizes

Frequently Asked Questions

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