What is the catalog number for MITF Antibody?

The catalog number for MITF Antibody is orb750140.

What sizes are available for MITF Antibody?

MITF Antibody is available in the following size(s): 20 µg, 100 µg.

How many pack sizes does MITF Antibody come in?

MITF Antibody is available in 2 different pack sizes.

Is MITF Antibody in stock?

MITF Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MITF Antibody

MITF (microphthalmia transcription factor) is a transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR) . Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1) . Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. [UniProt]

Product Specifications

UniProt

O75030

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the MITF antibody.

Clonality

Monoclonal

Clone

MPAF3

Conjugation

Unconjugated

Field of Research

Stem Cell & Developmental Biology

Purification

Protein G affinity chromatography

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Titering of the MITF antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.