AMG 487 (S-enantiomer)
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3.
Product Specifications
CAS Number
473720-30-8
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/AMG-487-S-enantiomer.html
Concentration
10mM
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N([C@@H](C)C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5
Molecular Formula
C32H28F3N5O4
Molecular Weight
603.59
Precautions
H302, H315, H319, H335
References & Citations
[1]CXCR3 ANTAGONISTS. WIPO Patent Application WO/2002/083143
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CXCR3
Available Sizes
Frequently Asked Questions
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