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AMG 487 (S-enantiomer)

AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an antagonist of the chemokine receptor CXCR3.

Product Specifications

CAS Number

[473720-30-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

CXCR

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/AMG-487-S-enantiomer.html

Concentration

10mM

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N([C@@H](C)C1=NC2=NC=CC=C2C(N1C3=CC=C(OCC)C=C3)=O)CC4=CC=CN=C4)CC5=CC=C(OC(F)(F)F)C=C5

Molecular Formula

C32H28F3N5O4

Molecular Weight

603.59

Precautions

H302, H315, H319, H335

References & Citations

[1]CXCR3 ANTAGONISTS. WIPO Patent Application WO/2002/083143

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CXCR3

Available Sizes

Curated Selection

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