Nuvenzepine

Nuvenzepine is an mAChR antagonist, has the potential for gastrospasm treatment.

Product Specifications

CAS Number

[96487-37-5]

UNSPSC

12352005

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Nuvenzepine.html

Purity

99.67

Solubility

10 mM in DMSO

Smiles

O=C1C2=CC=CN=C2N(C(C3CCN(C)CC3)=O)C4=CC=CC=C4N1

Molecular Formula

C19H20N4O2

Molecular Weight

336.39

References & Citations

[1]Barocelli E, et al. Functional comparison between nuvenzepine and pirenzepine on different guinea pig isolated smooth muscle preparations. Pharmacol Res. 1994 Aug-Sep;30 (2) :161-70.|[2]Barocelli E, et al. Gastrointestinal activities of a new pirenzepine-analog, nuvenzepine, in the cat. Farmaco. 1990 Oct;45 (10) :1089-99.|[3]Caselli G, et al. Determination of nuvenzepine in human plasma by a sensitive [3H]pirenzepine radioreceptor binding assay. J Pharm Sci. 1991 Feb;80 (2) :173-7.