What is the catalog number for NKX2.2 Antibody?

The catalog number for NKX2.2 Antibody is orb534029.

What sizes are available for NKX2.2 Antibody?

NKX2.2 Antibody is available in the following size(s): 20 µg, 100 µg.

How many pack sizes does NKX2.2 Antibody come in?

NKX2.2 Antibody is available in 2 different pack sizes.

Is NKX2.2 Antibody in stock?

NKX2.2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

NKX2.2 Antibody

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Product Specifications

UniProt

O95096

Reactivity

Human

Immunogen

A human partial recombinant protein corresponding to amino acids 1-119 was used as the immunogen for this NKX2.2 antibody.

Clonality

Monoclonal

Clone

RMNK2-2

Conjugation

Unconjugated

Field of Research

Stem Cell & Developmental Biology

Purification

Protein G affinity chromatography

Dilution

Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT, Prediluted IHC only format : incubate for 30 min at RT (1)

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Titering of the NKX2.2 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.