1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine (sodium)

Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product generated following activation of the NADPH oxidase and lyso-PS signaling. Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium through the macrophage G2A functions to enhance existing receptor/ligand systems for resolution of neutrophilic inflammation[1].

Product Specifications

CAS Number

[326589-90-6]

Product Name Alternative

18:1 Lyso-PS

UNSPSC

12352211

Target

NADPH Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/1-oleoyl-2-hydroxy-sn-glycero-3-phospho-l-serine-sodium.html

Purity

99.0

Solubility

H2O : ≥ 100 mg/mL

Smiles

N[C@@H](COP(O)(OC[C@H](O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O)C(O[Na])=O

Molecular Formula

C24H45NNaO9P

Molecular Weight

545.58

References & Citations

[1]Frasch SC, et, al. NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A. J Biol Chem. 2008 Nov 28;283 (48) :33736-49.