FLCN Recombinant Rabbit Monoclonal Antibody [PSH07-68]
The tumor suppressor gene FLCN encodes the protein folliculin, also known as Birt–Hogg–Dubé syndrome protein, which functions as an inhibitor of Lactate Dehydrogenase-A and a regulator of the Warburg effect. Folliculin (FLCN) is also associated with Birt–Hogg–Dubé syndrome, which is an autosomal dominant inherited cancer syndrome in which affected individuals are at risk for the development of benign cutaneous tumors (folliculomas), pulmonary cysts (often associated with pneumothorax), and kidney tumors.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
FLCN, BHD
Swiss Prot
Q8NFG4 Human, Q8QZS3 Mouse, Q76JQ2 Rat
Cellular Locus
Lysosome membrane, Cytoplasm, cytosol, Cell projection, cilium, , cytoskeleton, microtubule organizing center, centrosome, spindle, Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within human FLCN aa 1-50.
Isotype
IgG
Clone
PSH07-68
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
U-2 OS cell lysate, NIH/3T3 cell lysate, C6 cell lysate, mouse brain tissue, U-2 OS, NIH/3T3, C6.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:2,000 ;IF-Cell: 1:100 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 64 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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