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Linearmycin A

Linearmycin A is a polyene antibiotic that has been found in Streptomyces. It is active against the bacteria S. aureus and E. coli (MICs=3.1 and 1.6 μg/disc, respectively), the fungi S. cerevisiae and C. albicans (MICs=0.1 and 1.6 μg/disc, respectively), and the plant pathogenic fungus A. niger in disc assays (MIC=0.2 μg/disc) . Linearmycin A induces lysis and degradation of B. subtilis as a component of Streptomyces Mg1 extract.

Product Specifications

CAS Number

[163596-98-3]

UNSPSC

12352211

Target

Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/linearmycin-a.html

Smiles

OC(/C(C)=C/C=C/C=C/C=C/CC/C=C/C(C)[C@H](O)[C@@H](C)[C@H](O)/C=C/C=C/C=C/C=C/C=C/CC(O)C(C)C(CC(O)C[C@H](O)C[C@H](O)/C=C/C[C@@H](O)C[C@H](O)C[C@@H](O)C[C@H](O)/C=C/CC(O)/C=C/C[C@H](O)C[C@H](O)CCCN)=O)=O

Molecular Formula

C64H101NO16

Molecular Weight

1140.48

References & Citations

[1]Sakuda, et al. Novel linear polyene antibiotics: Linearmycins. J. Chem. Soc. Perkin 1 18, 2315-2319 (1996) .

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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