Disuccinimidyl sulfoxide

Disuccinimidyl sulfoxide (DSSO) is a mass spectrometry (MS) -cleavable cross-linker that is applicable for model peptides and proteins and a multisubunit protein complex. Disuccinimidyl sulfoxide contains two symmetric collision-induced dissociation (CID) -cleavable sites for identification of DSSO-cross-linked peptides based their distinct fragmentation patterns[1].

Product Specifications

CAS Number

[1351828-03-9]

Product Name Alternative

DSSO

UNSPSC

12352005

Hazard Statement

H242

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/disuccinimidyl-sulfoxide.html

Purity

99.83

Solubility

DMF : 10 mg/mL (ultrasonic; warming) |DMSO : 20 mg/mL (ultrasonic; warming)

Smiles

O=C(ON1C(CCC1=O)=O)CCS(CCC(ON2C(CCC2=O)=O)=O)=O

Molecular Formula

C14H16N2O9S

Molecular Weight

388.35

Precautions

H242

References & Citations

[1]Kao A, et al., Development of a novel cross-linking strategy for fast and accurate identification of cross-linked peptides of protein complexes. Mol Cell Proteomics. 2011 Jan;10 (1) :M110.002212.