Satratoxin G

Satratoxin G is a large cyclic mucor toxin. Satratoxin G induces apoptosis by activation of caspase [1][2].

Product Specifications

CAS Number

[53126-63-9]

UNSPSC

12352005

Hazard Statement

H302+H312+H332

Target

Apoptosis; Caspase

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/satratoxin-g.html

Purity

99.52

Solubility

10 mM in DMSO

Smiles

CC1=C[C@]2([H])[C@]([C@]3(C)[C@@]4(OC4)[C@](C[C@H]3OC(/C=C\C=C\[C@@]5(C(O)C)[C@H](O)[C@@]6(C7O6)CCO5)=O)([H])O2)(COC7=O)CC1

Molecular Formula

C29H36O10

Molecular Weight

544.59

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Nagase M, et al. Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3. Immunol Lett. 2002 Oct 21;84 (1) :23-7.|[2]Islam Z, et al. Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain. Environ Health Perspect. 2006 Jul;114 (7) :1099-107.