Abl Cytosolic Substrate

Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl) . Abl Protein Tyrosine Kinase (AbI) is a truncated form of the v-AbI Protein Tyrosine Kinase, a partner in the Gag-Abl fusion protein of the Abelson murine leukemia virus[1].

Product Specifications

CAS Number

[168202-46-8]

Product Name Alternative

Abltide

UNSPSC

12352209

Target

Bcr-Abl

Type

Peptides

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/abl-cytosolic-substrate.html

Purity

99.60

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(O)=O)N

Molecular Formula

C64H101N15O16

Molecular Weight

1336.58

References & Citations

[1]Buchdunger E, et al. Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res. 1996 Jan 1;56 (1) :100-4.