Human Recombinant TNFRSF7/CD27 Extracellular Domain

<strong>Human Recombinant TNFRSF7/CD27 Extracellular Domain </strong>_x000D_ <strong>Catalog number:</strong> B2016998_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 47.2 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> TNFRSF7, TNFRSF7, Tumor Necrosis Factor Receptor Superfamily Receptor 7_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Teplyakov A, Obmolova G, Malia TJ, Gilliland GL. Crystal structure of CD27 in complex with a neutralizing noncompeting antibody Acta Crystallogr F Struct Biol Commun. 2017 May 1;73(Pt 5):294-299._x000D_ 2: Han Y, Xie W, Song DG, Powell DJ Jr. Control of triple-negative breast cancer using ex vivo self-enriched, costimulated NKG2D CAR T cells J Hematol Oncol. 2018 Jul 6;11(1):92._x000D_ 3: Goodwin RG, Alderson MR, Smith CA, Armitage RJ, VandenBos T, Jerzy R, Tough TW, Schoenborn MA, Davis-Smith T, Hennen K, et al. Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor Cell. 1993 May 7;73(3):447-56._x000D_ 4: Marsters SA, Frutkin AD, Simpson NJ, Fendly BM, Ashkenazi A. Identification of cysteine-rich domains of the type 1 tumor necrosis factor receptor involved in ligand binding J Biol Chem. 1992 Mar 25;267(9):5747-50._x000D_ 5: Calderhead DM, Buhlmann JE, van den Eertwegh AJ, Claassen E, Noelle RJ, Fell HP. Cloning of mouse Ox40: a T cell activation marker that may mediate T-B cell interactions J Immunol. 1993 Nov 15;151(10):5261-71._x000D_ 6: Taylor L, Bachler M, Duncan I, Keen S, Fallon R, Mair C, McDonald TT, Schwarz H. In vitro and in vivo activities of OX40 (CD134)-IgG fusion protein isoforms with different levels of immune-effector functions J Leukoc Biol. 2002 Sep;72(3):522-9._x000D_ 7: Lian J, Yue Y, Yu W, Zhang Y. Immunosenescence: a key player in cancer development J Hematol Oncol. 2020 Nov 10;13(1):151._x000D_ 8: Budeus B, Kibler A, Küppers R. Human IgM-expressing memory B cells Front Immunol. 2023 Dec 8;14:1308378._x000D_ 9: Cohen AD, Garfall AL, Stadtmauer EA, Melenhorst JJ, Lacey SF, Lancaster E, Vogl DT, Weiss BM, Dengel K, Nelson A, Plesa G, Chen F, Davis MM, Hwang WT, Young RM, Brogdon JL, Isaacs R, Pruteanu-Malinici I, Siegel DL, Levine BL, June CH, Milone MC. B cell maturation antigen-specific CAR T cells are clinically active in multiple myeloma J Clin Invest. 2019 Mar 21;129(6):2210-2221._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20023635">10: Kwakkenbos MJ, Diehl SA, Yasuda E, Bakker AQ, van Geelen CM, Lukens MV, van Bleek GM, Widjojoatmodjo MN, Bogers WM, Mei H, Radbruch A, Scheeren FA, Spits H, Beaumont T. Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming Nat Med. 2010 Jan;16(1):123-8. </a>_x000D_ _x000D_ <strong>Products Related to Human Recombinant TNFRSF7/CD27 Extracellular Domain can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>