9-cis-Retinol-d5

9-cis-Retinol-d5 is deuterium labeled 9-cis Retinol. 9-cis Retinol is a precursor of 9-cis-Retinal (HY-W009310) . 9-cis Retinol can inhibit 9-cis-Retinoic acid (HY-15128) synthesis in Hep G2 cells[1][2].

Product Specifications

UNSPSC

12352211

Hazard Statement

H315-H319-H335

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology

Smiles

CC1(C(/C=C(/C(C([2H])([2H])[2H])=C(\C=C\C(C)=C\CO)[2H])[2H])=C(CCC1)C)C

Molecular Formula

C20H25D5O

Molecular Weight

291.48

Precautions

P261-P280-P338-P340-P351-P352

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Paik J, et, al. 9-cis-retinoids: biosynthesis of 9-cis-retinoic acid. Biochemistry. 2000 Jul 11;39 (27) :8073-84.